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Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis

We have investigated the function of mitotic kinesin-like protein (MKlp) 2, a kinesin localized to the central spindle, and demonstrate that its depletion results in a failure of cleavage furrow ingression and cytokinesis, and disrupts localization of polo-like kinase 1 (Plk1). MKlp2 is a target for...

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Detalles Bibliográficos
Autores principales:	Neef, Rüdiger, Preisinger, Christian, Sutcliffe, Josephine, Kopajtich, Robert, Nigg, Erich A., Mayer, Thomas U., Barr, Francis A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172827/ https://www.ncbi.nlm.nih.gov/pubmed/12939256 http://dx.doi.org/10.1083/jcb.200306009

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