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Clathrin-mediated endocytosis in AP-2–depleted cells
We have used RNA interference to knock down the AP-2 μ2 subunit and clathrin heavy chain to undetectable levels in HeLaM cells. Clathrin-coated pits associated with the plasma membrane were still present in the AP-2–depleted cells, but they were 12-fold less abundant than in control cells. No clathr...
Autores principales: | Motley, Alison, Bright, Nicholas A., Seaman, Matthew N.J., Robinson, Margaret S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172830/ https://www.ncbi.nlm.nih.gov/pubmed/12952941 http://dx.doi.org/10.1083/jcb.200305145 |
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