Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

Bone morphogenetic proteins (BMPs) regulate multiple cellular processes, including cell differentiation and migration. Their signals are transduced by the kinase receptors BMPR-I and BMPR-II, leading to Smad transcription factor activation via BMPR-I. LIM kinase (LIMK) 1 is a key regulator of actin...

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Detalles Bibliográficos
Autores principales: Foletta, Victoria C., Lim, Mei Ann, Soosairajah, Juliana, Kelly, April P., Stanley, Edouard G., Shannon, Mark, He, Wei, Das, Supratik, Massagué, Joan, Bernard, Ora
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172847/
https://www.ncbi.nlm.nih.gov/pubmed/12963706
http://dx.doi.org/10.1083/jcb.200212060

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