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Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis

During puberty, mouse mammary epithelial ducts invade the stromal mammary fat pad in a wave of branching morphogenesis to form a complex ductal tree. Using pharmacologic and genetic approaches, we find that mammary gland branching morphogenesis requires transient matrix metalloproteinase (MMP) activ...

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Detalles Bibliográficos
Autores principales:	Wiseman, Bryony S., Sternlicht, Mark D., Lund, Leif R., Alexander, Caroline M., Mott, Joni, Bissell, Mina J., Soloway, Paul, Itohara, Shigeyoshi, Werb, Zena
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172848/ https://www.ncbi.nlm.nih.gov/pubmed/12975354 http://dx.doi.org/10.1083/jcb.200302090

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