Juxtaparanodal clustering of Shaker-like K(+) channels in myelinated axons depends on Caspr2 and TAG-1

In myelinated axons, K(+) channels are concealed under the myelin sheath in the juxtaparanodal region, where they are associated with Caspr2, a member of the neurexin superfamily. Deletion of Caspr2 in mice by gene targeting revealed that it is required to maintain K(+) channels at this location. Fu...

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Detalles Bibliográficos
Autores principales: Poliak, Sebastian, Salomon, Daniela, Elhanany, Hadas, Sabanay, Helena, Kiernan, Brent, Pevny, Larysa, Stewart, Colin L., Xu, Xiaorong, Chiu, Shing-Yan, Shrager, Peter, Furley, Andrew J.W., Peles, Elior
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172860/
https://www.ncbi.nlm.nih.gov/pubmed/12963709
http://dx.doi.org/10.1083/jcb.200305018

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