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Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response

Infection with the human microbial pathogen Helicobacter pylori is assumed to lead to invasive gastric cancer. We find that H. pylori activates the hepatocyte growth factor/scatter factor receptor c-Met, which is involved in invasive growth of tumor cells. The H. pylori effector protein CagA intrace...

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Detalles Bibliográficos
Autores principales: Churin, Yuri, Al-Ghoul, Laila, Kepp, Oliver, Meyer, Thomas F., Birchmeier, Walter, Naumann, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172921/
https://www.ncbi.nlm.nih.gov/pubmed/12719469
http://dx.doi.org/10.1083/jcb.200208039