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Regulation of β cell glucokinase by S-nitrosylation and association with nitric oxide synthase

Glucokinase (GK) activity plays a key role in glucose-stimulated insulin secretion from pancreatic β cells. Insulin regulates GK activity by modulating its association with secretory granules, although little is known about the mechanisms involved in regulating this association. Using quantitative i...

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Detalles Bibliográficos
Autores principales: Rizzo, Megan A., Piston, David W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172922/
https://www.ncbi.nlm.nih.gov/pubmed/12707306
http://dx.doi.org/10.1083/jcb.200301063

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