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Neural cell adhesion molecule (NCAM) association with PKCβ(2) via βI spectrin is implicated in NCAM-mediated neurite outgrowth

In hippocampal neurons and transfected CHO cells, neural cell adhesion molecule (NCAM) 120, NCAM140, and NCAM180 form Triton X-100–insoluble complexes with βI spectrin. Heteromeric spectrin (αIβI) binds to the intracellular domain of NCAM180, and isolated spectrin subunits bind to both NCAM180 and N...

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Detalles Bibliográficos
Autores principales:	Leshchyns'ka, Iryna, Sytnyk, Vladimir, Morrow, Jon S., Schachner, Melitta
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172933/ https://www.ncbi.nlm.nih.gov/pubmed/12743109 http://dx.doi.org/10.1083/jcb.200303020

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