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Modeling network dynamics: the lac operon, a case study
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, wh...
Autores principales: | Vilar, José M.G., Guet, Călin C., Leibler, Stanislas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172934/ https://www.ncbi.nlm.nih.gov/pubmed/12743100 http://dx.doi.org/10.1083/jcb.200301125 |
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