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PMN transendothelial migration decreases nuclear NFκB in IL-1β–activated endothelial cells: role of PECAM-1
During the systemic inflammatory response, circulating cytokines interact with the vascular endothelium, resulting in activation and nuclear accumulation of the nuclear transcription factor, nuclear factor kappa B (NFκB). In turn, NFκB transactivates relevant proinflammatory genes, resulting in an a...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172941/ https://www.ncbi.nlm.nih.gov/pubmed/12743110 http://dx.doi.org/10.1083/jcb.200212048 |