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Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice
Tight junctions are well-developed between adjacent endothelial cells of blood vessels in the central nervous system, and play a central role in establishing the blood-brain barrier (BBB). Claudin-5 is a major cell adhesion molecule of tight junctions in brain endothelial cells. To examine its possi...
Autores principales: | Nitta, Takehiro, Hata, Masaki, Gotoh, Shimpei, Seo, Yoshiteru, Sasaki, Hiroyuki, Hashimoto, Nobuo, Furuse, Mikio, Tsukita, Shoichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172943/ https://www.ncbi.nlm.nih.gov/pubmed/12743111 http://dx.doi.org/10.1083/jcb.200302070 |
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