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Rapid exchange of mammalian topoisomerase IIα at kinetochores and chromosome arms in mitosis

Astable cell line (GT2-LPk) derived from LLC-Pk was created in which endogenous DNA topoisomerase IIα (topoIIα) protein was downregulated and replaced by the expression of topoIIα fused with enhanced green fluorescent protein (EGFP–topoIIα). The EGFP–topoIIα faithfully mimicked the distribution of t...

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Detalles Bibliográficos
Autores principales:	Tavormina, Penny A., Côme, Marie-George, Hudson, Joanna R., Mo, Yin-Yuan, Beck, William T., Gorbsky, Gary J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173008/ https://www.ncbi.nlm.nih.gov/pubmed/12105179 http://dx.doi.org/10.1083/jcb.200202053

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