Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites

Downstream of kinase (Dok)–related protein (DokR, also known as p56(dok)/FRIP/Dok-R) is implicated in cytokine and immunoreceptor signaling in myeloid and T cells. Tyrosine phosphorylation induces DokR to bind the signal relay molecules, RasGTPase-activating protein (RasGAP) and Nck. Here, we have e...

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Detalles Bibliográficos
Autores principales: Gugasyan, Raffi, Quilici, Cathy, I, Stacey T.T., Grail, Dianne, Verhagen, Anne M., Roberts, Andrew, Kitamura, Toshio, Dunn, Ashley R., Lock, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173016/
https://www.ncbi.nlm.nih.gov/pubmed/12093790
http://dx.doi.org/10.1083/jcb.200112066

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