Cargando…

Tiny dancers: the integrin–growth factor nexus in angiogenic signaling

A vital step in growth factor–driven angiogenesis is the coordinated engagement of endothelial integrins with the extracellular matrix. The molecular mechanisms that partner growth factors and integrins are being elucidated, revealing an intricate interaction of surface receptors and their signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Smyth, Susan S., Patterson, Cam
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173020/
https://www.ncbi.nlm.nih.gov/pubmed/12105178
http://dx.doi.org/10.1083/jcb.200202100
Descripción
Sumario:A vital step in growth factor–driven angiogenesis is the coordinated engagement of endothelial integrins with the extracellular matrix. The molecular mechanisms that partner growth factors and integrins are being elucidated, revealing an intricate interaction of surface receptors and their signaling pathways.