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The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import
The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells. Eight filaments project from the NPC into the cytoplasm and are proposed to function in nuclear import. We investigated the localization and function of two nucleoporin...
Autores principales: | Walther, Tobias C., Pickersgill, Helen S., Cordes, Volker C., Goldberg, Martin W., Allen, Terry D., Mattaj, Iain W., Fornerod, Maarten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173022/ https://www.ncbi.nlm.nih.gov/pubmed/12105182 http://dx.doi.org/10.1083/jcb.200202088 |
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