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The face of TSR revealed: an extracellular signaling domain is exposed
In this issue, Tan et al. (2002) report the first high resolution (1.9 Å) structural data for thrombospondin (TSP)-1, a large multifunctional protein that regulates cell adhesion, angiogenesis, cell proliferation and survival, TGFβ activation, and protease function (for review see Chen et al., 2000)...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173053/ https://www.ncbi.nlm.nih.gov/pubmed/12403807 http://dx.doi.org/10.1083/jcb.200209138 |