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Hsc70 is required for endocytosis and clathrin function in Drosophila

By screening for Drosophila mutants exhibiting aberrant bride of sevenless (Boss) staining patterns on eye imaginal disc epithelia, we have recovered a point mutation in Hsc70-4, the closest homologue to bovine clathrin uncoating ATPase. Although the mutant allele was lethal, analysis of mutant clon...

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Detalles Bibliográficos
Autores principales: Chang, Henry C., Newmyer, Sherri L., Hull, Michael J., Ebersold, Melanie, Schmid, Sandra L., Mellman, Ira
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173062/
https://www.ncbi.nlm.nih.gov/pubmed/12427870
http://dx.doi.org/10.1083/jcb.200205086

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