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Cytoplasmic linker proteins promote microtubule rescue in vivo
The role of plus end–tracking proteins in regulating microtubule (MT) dynamics was investigated by expressing a dominant negative mutant that removed endogenous cytoplasmic linker proteins (CLIPs) from MT plus ends. In control CHO cells, MTs exhibited asymmetric behavior: MTs persistently grew towar...
Autores principales: | Komarova, Yulia A., Akhmanova, Anna S., Kojima, Shin-ichiro, Galjart, Niels, Borisy, Gary G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173097/ https://www.ncbi.nlm.nih.gov/pubmed/12446741 http://dx.doi.org/10.1083/jcb.200208058 |
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