Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration

RhoA activity is transiently inhibited at the initial phase of integrin engagement, when Cdc42- and/or Rac1-mediated membrane spreading and ruffling predominantly occur. Paxillin, an integrin-assembly protein, has four major tyrosine phosphorylation sites, and the phosphorylation of Tyr31 and Tyr118...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsubouchi, Asako, Sakakura, Junko, Yagi, Ryohei, Mazaki, Yuichi, Schaefer, Erik, Yano, Hajime, Sabe, Hisataka
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173105/
https://www.ncbi.nlm.nih.gov/pubmed/12446743
http://dx.doi.org/10.1083/jcb.200202117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173105/
https://www.ncbi.nlm.nih.gov/pubmed/12446743
http://dx.doi.org/10.1083/jcb.200202117

Ejemplares similares