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A phosphatidylinositol (4,5)-bisphosphate binding site within μ2-adaptin regulates clathrin-mediated endocytosis

The clathrin adaptor complex AP-2 serves to coordinate clathrin-coated pit assembly with the sorting of transmembrane cargo proteins at the plasmalemma. How precisely AP-2 assembly and cargo protein recognition at sites of endocytosis are regulated has remained unclear, but recent evidence implicate...

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Detalles Bibliográficos
Autores principales:	Rohde, Gundula, Wenzel, Dirk, Haucke, Volker
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173125/ https://www.ncbi.nlm.nih.gov/pubmed/12119359 http://dx.doi.org/10.1083/jcb.200203103

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