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DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts

Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the damage and activates the checkpoint is not yet und...

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Detalles Bibliográficos
Autores principales:	Stokes, Matthew P., Van Hatten, Ruth, Lindsay, Howard D., Michael, W. Matthew
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173144/ https://www.ncbi.nlm.nih.gov/pubmed/12213834 http://dx.doi.org/10.1083/jcb.200204127

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