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Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells
Cdc20 is a substrate adaptor and activator of the anaphase-promoting complex/cyclosome (APC/C), the E3 ubiquitin ligase whose activity is required for anaphase onset and exit from mitosis. A green fluorescent protein derivative, Cdc20–GFP, bound to centrosomes throughout the cell cycle and to kineto...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173153/ https://www.ncbi.nlm.nih.gov/pubmed/12196507 http://dx.doi.org/10.1083/jcb.200201135 |