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Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin
In Tetrahymena cells, phosphorylation of linker histone H1 regulates transcription of specific genes. Phosphorylation acts by creating a localized negative charge patch and phenocopies the loss of H1 from chromatin, suggesting that it affects transcription by regulating the dissociation of H1 from c...
Autores principales: | Dou, Yali, Bowen, Josephine, Liu, Yifan, Gorovsky, Martin A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173238/ https://www.ncbi.nlm.nih.gov/pubmed/12356861 http://dx.doi.org/10.1083/jcb.200202131 |
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