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Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1
The neurotropic virus, herpes simplex type 1 (HSV-1), inhibits the excitability of peripheral mammalian neurons, but the molecular mechanism of this effect has not been identified. Here, we use voltage-clamp measurement of ionic currents and an antibody against sodium channels to show that loss of e...
Autores principales: | Storey, Nina, Latchman, David, Bevan, Stuart |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173241/ https://www.ncbi.nlm.nih.gov/pubmed/12356869 http://dx.doi.org/10.1083/jcb.200204010 |
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