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Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility
Growth cone motility and guidance depend on the dynamic reorganization of filamentous actin (F-actin). In the growth cone, F-actin undergoes turnover, which is the exchange of actin subunits from existing filaments. However, the function of F-actin turnover is not clear. We used jasplakinolide (jasp...
Autores principales: | Gallo, Gianluca, Yee, Hal F., Letourneau, Paul C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173247/ https://www.ncbi.nlm.nih.gov/pubmed/12356866 http://dx.doi.org/10.1083/jcb.200204140 |
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