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Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
The COOH-terminal A168–170 region of the giant sarcomeric protein titin interacts with muscle-specific RING finger-1 (MURF-1). To investigate the functional significance of this interaction, we expressed green fluorescent protein fusion constructs encoding defined fragments of titin's M-line re...
Autores principales: | McElhinny, Abigail S., Kakinuma, Kazumi, Sorimachi, Hiroyuki, Labeit, Siegfried, Gregorio, Carol C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173255/ https://www.ncbi.nlm.nih.gov/pubmed/11927605 http://dx.doi.org/10.1083/jcb.200108089 |
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