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PECAM-1 (CD31) regulates a hydrogen peroxide–activated nonselective cation channel in endothelial cells
Hydrogen peroxide (H(2)O(2)) released by neutrophils is an important mediator of endothelial cell (EC) injury and vascular inflammation via its effect on EC-free Ca(2+), [Ca(2+)](i). Although the underlying mechanisms are not well understood, platelet endothelial cell adhesion molecule (PECAM)-1/CD-...
Autores principales: | Ji, Guangju, O'Brien, Christopher D., Feldman, Morris, Manevich, Yefim, Lim, Poay, Sun, Jing, Albelda, Steven M., Kotlikoff, Michael I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173260/ https://www.ncbi.nlm.nih.gov/pubmed/11927609 http://dx.doi.org/10.1083/jcb.200110056 |
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