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PECAM-1 (CD31) regulates a hydrogen peroxide–activated nonselective cation channel in endothelial cells

Hydrogen peroxide (H(2)O(2)) released by neutrophils is an important mediator of endothelial cell (EC) injury and vascular inflammation via its effect on EC-free Ca(2+), [Ca(2+)](i). Although the underlying mechanisms are not well understood, platelet endothelial cell adhesion molecule (PECAM)-1/CD-...

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Detalles Bibliográficos
Autores principales: Ji, Guangju, O'Brien, Christopher D., Feldman, Morris, Manevich, Yefim, Lim, Poay, Sun, Jing, Albelda, Steven M., Kotlikoff, Michael I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173260/
https://www.ncbi.nlm.nih.gov/pubmed/11927609
http://dx.doi.org/10.1083/jcb.200110056

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