The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1

Întegrins, matrix metalloproteases (MMPs), and the cytokine TGF-β have each been implicated in homeostatic cell behaviors such as cell growth and matrix remodeling. TGF-β exists mainly in a latent state, and a major point of homeostatic control is the activation of TGF-β. Because the latent domain o...

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Detalles Bibliográficos
Autores principales: Mu, Dezhi, Cambier, Stephanie, Fjellbirkeland, Lars, Baron, Jody L., Munger, John S., Kawakatsu, Hisaaki, Sheppard, Dean, Broaddus, V. Courtney, Nishimura, Stephen L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173277/
https://www.ncbi.nlm.nih.gov/pubmed/11970960
http://dx.doi.org/10.1083/jcb.200109100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173277/
https://www.ncbi.nlm.nih.gov/pubmed/11970960
http://dx.doi.org/10.1083/jcb.200109100

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