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Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing

To examine the involvement of interchromatin granule clusters (IGCs) in transcription and pre-mRNA splicing in mammalian cell nuclei, the serine-arginine (SR) protein kinase cdc2-like kinase (Clk)/STY was used as a tool to manipulate IGC integrity in vivo. Both immunofluorescence and transmission el...

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Detalles Bibliográficos
Autores principales:	Sacco-Bubulya, Paula, Spector, David L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173333/ https://www.ncbi.nlm.nih.gov/pubmed/11827980 http://dx.doi.org/10.1083/jcb.200107017

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