Cargando…
The importin-β binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro
The nuclear localization signal (NLS) of spliceosomal U snRNPs is composed of the U snRNA's 2,2,7-trimethyl-guanosine (m(3)G)-cap and the Sm core domain. The m(3)G-cap is specifically bound by snurportin1, which contains an NH(2)-terminal importin-β binding (IBB) domain and a COOH-terminal m(3)...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173342/ https://www.ncbi.nlm.nih.gov/pubmed/11815630 http://dx.doi.org/10.1083/jcb.200108114 |