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A role of topoisomerase II in linking DNA replication to chromosome condensation
The condensin complex and topoisomerase II (topo II) have different biochemical activities in vitro, and both are required for mitotic chromosome condensation. We have used Xenopus egg extracts to investigate the functional interplay between condensin and topo II in chromosome condensation. When unr...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173373/ https://www.ncbi.nlm.nih.gov/pubmed/12604590 http://dx.doi.org/10.1083/jcb.200209023 |