Cargando…

The cysteine-rich domain regulates ADAM protease function in vivo

ADAMs are membrane-anchored proteases that regulate cell behavior by proteolytically modifying the cell surface and ECM. Like other membrane-anchored proteases, ADAMs contain candidate “adhesive” domains downstream of their metalloprotease domains. The mechanism by which membrane-anchored cell surfa...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Katherine M., Gaultier, Alban, Cousin, Helene, Alfandari, Dominique, White, Judith M., DeSimone, Douglas W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173380/
https://www.ncbi.nlm.nih.gov/pubmed/12460986
http://dx.doi.org/10.1083/jcb.200206023