ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

The small GTPase Rho acts on two effectors, ROCK and mDia1, and induces stress fibers and focal adhesions. However, how ROCK and mDia1 individually regulate signals and dynamics of these structures remains unknown. We stimulated serum-starved Swiss 3T3 fibroblasts with LPA and compared the effects o...

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Detalles Bibliográficos
Autores principales: Tsuji, Takahiro, Ishizaki, Toshimasa, Okamoto, Muneo, Higashida, Chiharu, Kimura, Kazuhiro, Furuyashiki, Tomoyuki, Arakawa, Yoshiki, Birge, Raymond B., Nakamoto, Tetsuya, Hirai, Hisamaru, Narumiya, Shuh
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173402/
https://www.ncbi.nlm.nih.gov/pubmed/12021256
http://dx.doi.org/10.1083/jcb.200112107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173402/
https://www.ncbi.nlm.nih.gov/pubmed/12021256
http://dx.doi.org/10.1083/jcb.200112107

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