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TGFβ induces GDNF responsiveness in neurons by recruitment of GFRα1 to the plasma membrane
We have previously shown that the neurotrophic effect of glial cell line–derived neurotrophic factor (GDNF) in vitro and in vivo requires the presence of transforming growth factor (TGF)β. Using primary neurons (chick E8 ciliary) we show that the combination of GDNF plus TGFβ promotes survival, wher...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173495/ https://www.ncbi.nlm.nih.gov/pubmed/12370242 http://dx.doi.org/10.1083/jcb.200203115 |