Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome

Ubiquitin (Ub) attachment to cell surface proteins causes their lysosomal degradation by incorporating them into lumenal membranes of multivesicular bodies (MVBs). Two yeast endosomal protein complexes have been proposed as Ub-sorting “receptors,” the Vps27-Hse1 complex and the ESCRT-I complex. We u...

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Detalles Bibliográficos
Autores principales: Bilodeau, Patricia S., Winistorfer, Stanley C., Kearney, William R., Robertson, Andrew D., Piper, Robert C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173515/
https://www.ncbi.nlm.nih.gov/pubmed/14581452
http://dx.doi.org/10.1083/jcb.200305007

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