Cargando…

Talin1 is critical for force-dependent reinforcement of initial integrin–cytoskeleton bonds but not tyrosine kinase activation

Cells rapidly transduce forces exerted on extracellular matrix contacts into tyrosine kinase activation and recruitment of cytoskeletal proteins to reinforce integrin–cytoskeleton connections and initiate adhesion site formation. The relationship between these two processes has not been defined, par...

Descripción completa

Detalles Bibliográficos
Autores principales: Giannone, Grégory, Jiang, Guoying, Sutton, Deborah H., Critchley, David R., Sheetz, Michael P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173516/
https://www.ncbi.nlm.nih.gov/pubmed/14581461
http://dx.doi.org/10.1083/jcb.200302001

Ejemplares similares