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Role of the pleckstrin homology domain of PLCγ1 in its interaction with the insulin receptor

A thiol-reactive membrane-associated protein (TRAP) binds covalently to the cytoplasmic domain of the human insulin receptor (IR) β-subunit when cells are treated with the homobifunctional cross-linker reagent 1,6-bismaleimidohexane. Here, TRAP was found to be phospholipase C γ1 (PLCγ1) by mass spec...

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Detalles Bibliográficos
Autores principales:	Kwon, Yong-Kook, Jang, Hyeung-Jin, Kole, Sutapa, He, Hua-Jun, Bernier, Michel
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173518/ https://www.ncbi.nlm.nih.gov/pubmed/14568990 http://dx.doi.org/10.1083/jcb.200301131

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