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MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments

MAP2 and tau exhibit microtubule-stabilizing activities that are implicated in the development and maintenance of neuronal axons and dendrites. The proteins share a homologous COOH-terminal domain, composed of three or four microtubule binding repeats separated by inter-repeats (IRs). To investigate...

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Detalles Bibliográficos
Autores principales: Al-Bassam, Jawdat, Ozer, Rachel S., Safer, Daniel, Halpain, Shelley, Milligan, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173547/
https://www.ncbi.nlm.nih.gov/pubmed/12082079
http://dx.doi.org/10.1083/jcb.200201048