Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1

Progress through mitosis is controlled by the sequential destruction of key regulators including the mitotic cyclins and securin, an inhibitor of anaphase whose destruction is required for sister chromatid separation. Here we have used live cell imaging to determine the exact time when human securin...

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Detalles Bibliográficos
Autores principales: Hagting, Anja, den Elzen, Nicole, Vodermaier, Hartmut C., Waizenegger, Irene C., Peters, Jan-Michael, Pines, Jonathon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173548/
https://www.ncbi.nlm.nih.gov/pubmed/12070128
http://dx.doi.org/10.1083/jcb.200111001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173548/
https://www.ncbi.nlm.nih.gov/pubmed/12070128
http://dx.doi.org/10.1083/jcb.200111001

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