Cargando…

Sequential SNARE disassembly and GATE-16–GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion. Analysis of mammalian NSF function during cell-free assembly of Golgi ciste...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Joyce M.M., Shorter, James, Newman, Richard, Deinhardt, Katrin, Sagiv, Yuval, Elazar, Zvulun, Warren, Graham, Shima, David T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173554/
https://www.ncbi.nlm.nih.gov/pubmed/12070132
http://dx.doi.org/10.1083/jcb.200202082