Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

The rat homologue of a mitochondrial ATP-dependent protease Lon was cloned from cultured astrocytes exposed to hypoxia. Expression of Lon was enhanced in vitro by hypoxia or ER stress, and in vivo by brain ischemia. These observations suggested that changes in nuclear gene expression (Lon) triggered...

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Detalles Bibliográficos
Autores principales: Hori, Osamu, Ichinoda, Fusae, Tamatani, Takashi, Yamaguchi, Atsushi, Sato, Naoya, Ozawa, Kentaro, Kitao, Yasuko, Miyazaki, Mayuki, Harding, Heather P., Ron, David, Tohyama, Masaya, M Stern, David, Ogawa, Satoshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173558/
https://www.ncbi.nlm.nih.gov/pubmed/12082077
http://dx.doi.org/10.1083/jcb.200108103

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