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PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
Midzone microtubules of mammalian cells play an essential role in the induction of cell cleavage, serving as a platform for a number of proteins that play a part in cytokinesis. We demonstrate that PRC1, a mitotic spindle-associated Cdk substrate that is essential to cell cleavage, is a microtubule...
Autores principales: | Mollinari, Cristiana, Kleman, Jean-Philippe, Jiang, Wei, Schoehn, Guy, Hunter, Tony, Margolis, Robert L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173564/ https://www.ncbi.nlm.nih.gov/pubmed/12082078 http://dx.doi.org/10.1083/jcb.200111052 |
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