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Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell–cell adhesion
The Rho GTPase and Fyn tyrosine kinase have been implicated previously in positive control of keratinocyte cell–cell adhesion. Here, we show that Rho and Fyn operate along the same signaling pathway. Endogenous Rho activity increases in differentiating keratinocytes and is required for both Fyn kina...
Autores principales: | Calautti, Enzo, Grossi, Maddalena, Mammucari, Cristina, Aoyama, Yumi, Pirro, Maria, Ono, Yoshitaka, Li, Jie, Dotto, G. Paolo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173591/ https://www.ncbi.nlm.nih.gov/pubmed/11777936 http://dx.doi.org/10.1083/jcb.200105140 |
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