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IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients

Insulin-like growth factors (IGFs) are essential for skeletal muscle development, regeneration, and hypertrophy. Although autocrine actions of IGF-II are known to initiate myoblast differentiation, the regulatory elements and upstream signaling pathways for myogenic expression of IGF-II remain elusi...

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Detalles Bibliográficos
Autores principales: Erbay, Ebru, Park, In-Hyun, Nuzzi, Paul D., Schoenherr, Christopher J., Chen, Jie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173600/
https://www.ncbi.nlm.nih.gov/pubmed/14662739
http://dx.doi.org/10.1083/jcb.200307158