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ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments
Proteins in the ADF/cofilin (AC) family are essential for rapid rearrangements of cellular actin structures. They have been shown to be active in both the severing and depolymerization of actin filaments in vitro, but the detailed mechanism of action is not known. Under in vitro conditions, subunits...
Autores principales: | Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Shvetsov, Alexander, Reisler, Emil, Egelman, Edward H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173606/ https://www.ncbi.nlm.nih.gov/pubmed/14657234 http://dx.doi.org/10.1083/jcb.200308144 |
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