Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

Cleavage of membrane-anchored heparin-binding EGF-like growth factor (proHB-EGF) via metalloprotease activation yields amino- and carboxy-terminal regions (HB-EGF and HB-EGF-C, respectively), with HB-EGF widely recognized as a key element of epidermal growth factor receptor transactivation in G prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Nanba, Daisuke, Mammoto, Akiko, Hashimoto, Koji, Higashiyama, Shigeki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173632/
https://www.ncbi.nlm.nih.gov/pubmed/14597771
http://dx.doi.org/10.1083/jcb.200303017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173632/
https://www.ncbi.nlm.nih.gov/pubmed/14597771
http://dx.doi.org/10.1083/jcb.200303017

Ejemplares similares