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ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

Breast epithelial cells differentiate into tubules when cultured in floating three-dimensional (3D) collagen gels, but not when the cells are cultured in the same collagen matrix that is attached to the culture dish. These observations suggest that the biophysical properties of collagenous matrices...

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Detalles Bibliográficos
Autores principales: Wozniak, Michele A., Desai, Radhika, Solski, Patricia A., Der, Channing J., Keely, Patricia J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173660/
https://www.ncbi.nlm.nih.gov/pubmed/14610060
http://dx.doi.org/10.1083/jcb.200305010