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ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix
Breast epithelial cells differentiate into tubules when cultured in floating three-dimensional (3D) collagen gels, but not when the cells are cultured in the same collagen matrix that is attached to the culture dish. These observations suggest that the biophysical properties of collagenous matrices...
Autores principales: | Wozniak, Michele A., Desai, Radhika, Solski, Patricia A., Der, Channing J., Keely, Patricia J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173660/ https://www.ncbi.nlm.nih.gov/pubmed/14610060 http://dx.doi.org/10.1083/jcb.200305010 |
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