Cargando…
The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas
The SDF-1α/CXCR4 ligand/chemokine receptor pair is required for appropriate patterning during ontogeny and stimulates the growth and differentiation of critical cell types. Here, we demonstrate SDF-1α and CXCR4 expression in fetal pancreas. We have found that SDF-1α and its receptor CXCR4 are expres...
Autores principales: | Kayali, Ayse G., Van Gunst, Kurt, Campbell, Iain L., Stotland, Aleksandr, Kritzik, Marcie, Liu, Guoxun, Flodström-Tullberg, Malin, Zhang, You-Qing, Sarvetnick, Nora |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173676/ https://www.ncbi.nlm.nih.gov/pubmed/14638861 http://dx.doi.org/10.1083/jcb.200304153 |
Ejemplares similares
-
Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
por: Hill, Natasha J, et al.
Publicado: (2007) -
Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?
por: Blanter, Marfa, et al.
Publicado: (2019) -
Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins
por: Turkki, Paula, et al.
Publicado: (2020) -
The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells
por: Kayali, Ayse G., et al.
Publicado: (2012) -
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
por: Edlund, Anna, et al.
Publicado: (2014)