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Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1
Profilaggrin is a large epidermal polyprotein that is proteolytically processed during keratinocyte differentiation to release multiple filaggrin monomer units as well as a calcium-binding regulatory NH(2)-terminal filaggrin S-100 protein. We show that epidermal deficiency of the transmembrane serin...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173680/ https://www.ncbi.nlm.nih.gov/pubmed/14638864 http://dx.doi.org/10.1083/jcb.200304161 |